Research on the History of Lyme Disease generally leads to Plum Island. Plum Island Animal Disease Center of New York (PIADCNY) is a United States federal research facility dedicated to the study of animal diseases.
What Is Lyme Disease? New Findings Deepen the Mystery
http://news.nationalgeographic.com/news/2014/02/140228-lyme-disease-borrelia-burgdorferi-deer-tick-science/
"One theory—compelling but controversial—about the sudden emergence of the disease in Connecticut blames the accidental release of infected ticks during experiments at Plum Island Animal Disease Center, on Long Island Sound about eight miles south of Lyme."
Further Reading:
LDA Responds to CDC Limiting Lyme Disease Treatment
https://www.lymediseaseassociation.org/blog/1737-who-controls-fake-lyme-disease-news
US Government Admits Lyme Disease Is A Bioweapon
http://rense.com/general69/lyme.htm
Plum Island, Lyme Disease And Operation Paperclip - A Deadly Triangle
http://www.rense.com/general67/plumislandlyme.htm
Lyme Disease - A Biological Weapon?
http://www.rense.com/general63/lyme.htm